Slide 1: "Tumor Necrosis Factor (TNF), the TNF Receptor, and a Linear Model of Etanercept (Enbrel) is Shown with the lipid Membrane Removed " 360 x 240 pixels 12kb drawn freehand in 3dStudio Max
Slide 2: "A more three Dimensional Design (Model) for Etanercept (Enbrel) is shown " 360 x 240 pixels 15kb drawn freehand in 3dStudio Max
Slide 3: "TNF and Etanercept about to Bind " 360 x 240 pixels 7kb drawn freehand in 3dStudio Max
Tumor necrosis factor (TNF) and the endothelial cells TNF receptors are shown with the other lipid membrane structures removed. The linear construct of etanercept is replaced by a model with a more three dimensional design. The interaction of TNF with etanercept is shown. etanercept, infliximab, and adalimumab all work by sopping up TNF in the body fluids. The significant response of RA to various treatments tells us a lot about its pathophysiology. Clearly, excess proinflammatory mediators, such as tumor necrosis factor (TNF), are playing a profound role, as shown by effectiveness of the BRMs.
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Slide 4: "Etanercept (Enbrel) Binds to Tumor Necrosis Factor (TNF) " 360 x 240 pixels 11kb drawn freehand in 3dStudio Max ax
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