U.C.L.A. Rheumatology Pathophysiology of Disease Course Lecture, Second Year Medical School 2005

 
 
 
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Biologic Response Modifiers and the Innate Immune Response Part V Proinflammatory Cytokines, Rheumatoid Arthritis Joint, and Chronic Synovitis   Page 34
 
 
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The abnormal production of cytokines in the rheumatoid joint is animated.

Animation: Rheumatoid Joint
: The abnormal production of cytokines in the rheumatoid joint is animated.

Animation: Rheumatoid Joint
: The abnormal production of cytokines in the rheumatoid joint is animated.

Animation: Rheumatoid Joint
: The abnormal production of cytokines in the rheumatoid joint is animated.
 
       
Slide 1: "The Early Rheumatoid Joint before Evident Changes #1 " 360 x 240 pixels 17kb drawn freehand in 3dStudio Max Slide 2: "The Early Rheumatoid Joint before Evident Changes #2" 360 x 240 pixels 18kb drawn freehand in 3dStudio Max Slide 3: "The Early Rheumatoid Joint: Proinflammatory Cytokines are Secreted my Mononuclear Cells " 360 x 240 pixels 19kb drawn freehand in 3dStudio Max
Click Picture or here for larger slides (720 x 480 ) 48kb Click Picture or here for larger slides (720 x 480 ) 49kb Click Picture or here for larger slides (720 x 480 ) 49kb
      In the case of the described innate immune response, the inflammatory reaction, which occurs, will lead to elimination of the organism from the body and subsequent tissue repair. However, in rheumatoid arthritis, the inappropriate production of cytokines leads to the development of chronic synovitis.
 
   
 
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Slide 4: "Proinflammatory Cytokines Induce Synovitis in the Joint and Other Changes of Rheumatoid Arthritis " 360 x 240 pixels 17kb drawn freehand in 3dStudio Max
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Click Picture or here for larger slides (720 x480 ) 67kb
 
 
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