U.C.L.A. Rheumatology Pathophysiology of Disease Course Lecture, Second Year Medical School 2005

 
 
 
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Biologic Response Modifiers and the Innate Immune Response Part IV    Page 33  
 
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TNF is shown interacting with its receptor, leading to an intracellular signal.

Animation: Adhesion Molecules
: TNF is shown interacting with its receptor, leading to an intracellular signal.

Animation: Adhesion Molecules
: TNF is shown interacting with its receptor, leading to an intracellular signal.

Animation: Adhesion Molecules
: TNF is shown interacting with its receptor, leading to an intracellular signal.
 
       
Slide 21: "Endothelial Cells are Stimulated by Tumor Necrosis Factor (TNF) to Make and Present Adhesion Molecules #1" 360 x 240 pixels 15kb drawn freehand in 3dStudio Max Slide 22: "Endothelial Cells are Stimulated by Tumor Necrosis Factor (TNF) to Make and Present Adhesion Molecules #2" 360 x 240 pixels 28kb drawn freehand in 3dStudio Max Slide 23: "Endothelial Cells are Stimulated by Tumor Necrosis Factor (TNF) to Make and Present Adhesion Molecules #2" 360 x 240 pixels 28kb drawn freehand in 3dStudio Max
Click Picture or here for larger slides (720 x 480 ) 127kb Click Picture or here for larger slides (720 x 480 ) 58kb Click Picture or here for larger slides (720 x 480 ) 58kb
      The new adhesion molecules, in turn, are instrumental in directing passing neutrophils and other leukocytes to the site of infection, in the process of extravasation.
 
   
 
Slide 24: "The Poly Leaves the Blood Vessel " 360 x 240 pixels 19kb drawn freehand in 3dStudio Max Slide 25: "Extravasation By Diapedesis " 360 x 240 pixels 28kb drawn freehand in 3dStudio Max
Click Picture or here for larger slides (720 x480 ) 67kb Click Picture or here for larger slides (800 x 600 ) 117kb
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