Slide 15: "Tumor Necrosis Factor (TNF) shown above it Receptor" 360 x 240 pixels 28kb drawn freehand in 3dStudio Max
Slide 16: "Tumor Necrosis Factor (TNF) shown above it Receptor: Other Proteins Embedded in the Plasma Membrane are Noted " 360 x 240 pixels 42kb drawn freehand in 3dStudio Max
Slide 17: "The Cytoplasmic Portion of Tumor Necrosis Factor (TNF) Receptor are Shown " 360 x 240 pixels 36kb drawn freehand in 3dStudio Max
The interaction of TNF with its trimeric receptor complex on a target cell, in this case an endothelial cell, is depicted and results in a conformational change in the receptor molecules as shown. This conformational change permits the attachment of a docking molecule, which then interacts an activates an enzyme resulting in an intracellular signal, nuclear activation, transcription and translation, and ultimately leading to the insertion of new adhesion molecules on the cell's surface.
Slide 18: "An Adaptor or Scaffolding Molecule is shown. " 360 x 240 pixels 28kb drawn freehand in 3dStudio Max
Slide 19: "An Enzyme Attaches to the Adaptor Molecule " 360 x 240 pixels 27kb drawn freehand in 3dStudio Max
Slide 20: "The Enzyme is Shown Activating . " 360 x 240 pixels 28kb drawn freehand in 3dStudio Max
......Index 
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