U.C.L.A. Rheumatology Pathophysiology of Disease Course Lecture, Second Year Medical School 2005
 
 
 
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Inflammatory vs Non-Inflammatory Processes    Page 24
 
 
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Distinguishing inflammatory vs noninflammatory arthritis.
Animation: Inflammatory vs Not : Distinguishing inflammatory vs noninflammatory arthritis.
Animation: Inflammatory vs Not : Distinguishing inflammatory vs noninflammatory arthritis.
Animation: Inflammatory vs Not : Distinguishing inflammatory vs noninflammatory arthritis.
 
       
Slide 1: "Non-Inflammatory Arthritis: Osteoarthritis of the Hand " 360 x 240 pixels 15kb photo CAC Slide 2: " Osteoarthritis of the Hands with Pattern in Text Photo #1" 360 x 240 pixels 15kb photo CAC Slide 3: "Two Intensely Inflamed Feet are Shown " 400 x 300 pixels 18kb photo CAC Worked in 3dStudio Max
Click Picture or here for larger slides (720 x 480 ) 48kb Click Picture or here for larger slides (720 x 480 ) 43kb Click Picture or here for larger slides (800 x 500 ) 63kb
        I would now like to cover several different topics of interest.
         One of the first decisions that I try to make when dealing with a patient with arthritis is whether it is an inflammatory or noninflammatory problem. On examination this patients' joints are bony, and there is little evidence for inflammation.
         On the other hand, this foot is obviously intensely inflamed. Now I ask you whether you consider inflammation as a good or bad thing. And the answer should be it depends on several different factors. But in most of us, most of the time, inflammation is not only a good thing, but it is also lifesaving.
         Now this toe is also intensely inflamed. So both feet have severe arthritis. In the inflammatory response, as shown here, vessels near the inciting agent dilates, and the endothelial cells spread apart. These changes slow the flow of the blood, and allows for egress of proteins and cells that are critical for inflammatory response.
   
     
Slide 4: "A Blood Vessel Near a Focus of Inflammation is Shown " 400 x 300 pixels 20kb drawn freehand in 3dStudio Max Slide 5: "A Blood Vessel Near a Focus of Inflammation Dilates and the Cells Spread Apart" 400 x 300 pixels 23kb drawn freehand in 3dStudio Max
Click Picture or here for larger slides (800 x 500 ) 57kb Click Picture or here for larger slides (800 x 600 ) 66kb
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